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官方杂志> 严重烧伤的创面覆盖和修复重建:聚焦组织工程
严重烧伤的创面覆盖和修复重建:聚焦组织工程
      来源:Burns & Trauma

  当今医学技术已能挽救许多大面积烧伤病人的生命,然而,烧伤疤痕导致的外观和功能障碍仍然是一大难题。严重烧伤不仅损害皮肤,也常累及皮下脂肪甚至软骨等组织,临床上利用组织工程和再生医学技术治疗烧伤是当前的热点。Burns & Trauma最新刊出荷兰红十字医院烧伤中心Dr. Paul van Zuijlen教授的综述,系统阐述了组织工程技术在烧伤后创面覆盖和皮肤、脂肪、软骨组织重建方面的临床应用和最新进展,并对组织工程、干细胞疗法在此领域的未来做了展望,有助于读者全面了解这一领域的发展。



Review      


Tissue engineering in burn scar reconstruction


PPM van Zuijlen1234*, KLM Gardien134, MEH Jaspers1234, EJ Bos4, DC Baas1,AJM van Trier12 and E Middelkoop134


How to cite this article: PPM van Zuijlen, KLM Gardien, MEH Jaspers, EJ Bos, DC Baas, AJM van Teier and EMiddelkoop. Tissue engineering in burn scar recons truction. Burns &Trauma 2015, 3:18.


Abstract

Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

Keywords:

Burns; Tissue engineering; Scar; Contracture; Substitute; Subcutaneous fat tissue; Cartilage; Reconstruction